Details for gene set BIOCARTA_IL6_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	BIOCARTA_IL6_PATHWAY
Enrichment Score (ES)	0.4434479
Normalized Enrichment Score (NES)	1.5057015
Nominal p-value	0.065979384
FDR q-value	0.86751276
FWER p-Value	0.688

Fig 1: Enrichment plot: BIOCARTA_IL6_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Cebpb	Cebpb	1581	0.709	0.1078	Yes
2	Jun	Jun	2502	0.522	0.1976	Yes
3	Il6ra	Il6ra	4655	0.306	0.1820	Yes
4	Raf1	Raf1	5546	0.246	0.2049	Yes
5	Mapk3	Mapk3	5607	0.243	0.2622	Yes
6	Il6st	Il6st	5711	0.237	0.3163	Yes
7	Sos1	Sos1	6026	0.221	0.3574	Yes
8	Stat3	Stat3	6366	0.204	0.3933	Yes
9	Jak1	Jak1	6461	0.200	0.4386	Yes
10	Map2k1	Map2k1	7527	0.150	0.4304	Yes
11	Jak3	Jak3	8232	0.118	0.4296	Yes
12	Il6	Il6	8669	0.101	0.4360	Yes
13	Elk1	Elk1	9008	0.088	0.4434	Yes
14	Csnk2a2	Csnk2a2	9678	0.061	0.4302	No
15	Hras	Hras	10115	0.045	0.4228	No
16	Shc1	Shc1	10536	0.030	0.4124	No
17	Csnk2a1	Csnk2a1	10902	0.017	0.4012	No
18	Ptpn11	Ptpn11	11110	0.010	0.3949	No
19	Grb2	Grb2	11511	-0.004	0.3790	No
20	Srf	Srf	13411	-0.071	0.3161	No
21	Jak2	Jak2	15840	-0.168	0.2548	No
22	Fos	Fos	18750	-0.307	0.2073	No

Fig 2: BIOCARTA_IL6_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_IL6_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_IL6_PATHWAY