Details for gene set BIOCARTA_INSULIN_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	BIOCARTA_INSULIN_PATHWAY
Enrichment Score (ES)	0.49077663
Normalized Enrichment Score (NES)	1.5021257
Nominal p-value	0.08812261
FDR q-value	0.66777974
FWER p-Value	0.694

Fig 1: Enrichment plot: BIOCARTA_INSULIN_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Irs1	Irs1	1207	0.829	0.1328	Yes
2	Pik3r1	Pik3r1	1878	0.634	0.2452	Yes
3	Jun	Jun	2502	0.522	0.3347	Yes
4	Insr	Insr	3900	0.367	0.3570	Yes
5	Pik3ca	Pik3ca	5000	0.282	0.3730	Yes
6	Raf1	Raf1	5546	0.246	0.4045	Yes
7	Mapk3	Mapk3	5607	0.243	0.4558	Yes
8	Sos1	Sos1	6026	0.221	0.4871	Yes
9	Slc2a4	Slc2a4	7463	0.152	0.4602	Yes
10	Map2k1	Map2k1	7527	0.150	0.4908	Yes
11	Elk1	Elk1	9008	0.088	0.4477	No
12	Mapk8	Mapk8	9423	0.072	0.4462	No
13	Csnk2a2	Csnk2a2	9678	0.061	0.4490	No
14	Hras	Hras	10115	0.045	0.4405	No
15	Shc1	Shc1	10536	0.030	0.4293	No
16	Rasa1	Rasa1	10544	0.029	0.4355	No
17	Csnk2a1	Csnk2a1	10902	0.017	0.4243	No
18	Ptpn11	Ptpn11	11110	0.010	0.4178	No
19	Grb2	Grb2	11511	-0.004	0.4017	No
20	Srf	Srf	13411	-0.071	0.3371	No
21	Pik3cg	Pik3cg	14778	-0.126	0.3073	No
22	Fos	Fos	18750	-0.307	0.2073	No

Fig 2: BIOCARTA_INSULIN_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_INSULIN_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_INSULIN_PATHWAY