Details for gene set BIOCARTA_ERK_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___ClusterKO_vs_WT.RPKM_matrix___ClusterKO_vs_WT.cls #ClusterKO_versus_WT
Phenotype	RPKM_matrix___ClusterKO_vs_WT.cls#ClusterKO_versus_WT
Upregulated in class	ClusterKO
GeneSet	BIOCARTA_ERK_PATHWAY
Enrichment Score (ES)	0.7220575
Normalized Enrichment Score (NES)	1.3818405
Nominal p-value	0.0056710774
FDR q-value	0.042846568
FWER p-Value	0.236

Fig 1: Enrichment plot: BIOCARTA_ERK_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Pdgfra	na	661	1.468	0.0888	Yes
2	Ngfr	na	775	1.412	0.1835	Yes
3	Ngf	na	1196	1.230	0.2602	Yes
4	Rps6ka5	na	1668	1.078	0.3257	Yes
5	Elk1	na	3181	0.820	0.3550	Yes
6	Mapk3	na	3275	0.809	0.4088	Yes
7	Mapk1	na	4864	0.654	0.4253	Yes
8	Itgb1	na	5629	0.593	0.4523	Yes
9	Stat3	na	5875	0.576	0.4874	Yes
10	Map2k1	na	5879	0.576	0.5268	Yes
11	Igf1r	na	6159	0.556	0.5599	Yes
12	Mknk2	na	6499	0.533	0.5904	Yes
13	Grb2	na	6753	0.518	0.6214	Yes
14	Rps6ka1	na	7017	0.500	0.6510	Yes
15	Raf1	na	7937	0.447	0.6652	Yes
16	Mknk1	na	8095	0.438	0.6924	Yes
17	Ppp2ca	na	9343	0.368	0.6955	Yes
18	Shc1	na	9636	0.353	0.7145	Yes
19	Sos1	na	10413	0.312	0.7221	Yes
20	Egfr	na	13342	0.174	0.6820	No
21	Klk1b4	na	21089	0.003	0.5447	No
22	Klk1b3	na	43094	0.000	0.1543	No
23	Map2k2	na	51670	-0.105	0.0093	No
24	Gnas	na	52779	-0.170	0.0012	No
25	Myc	na	53324	-0.203	0.0055	No
26	Hras	na	53626	-0.230	0.0159	No
27	Ptprr	na	55680	-0.480	0.0124	No

Fig 2: BIOCARTA_ERK_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_ERK_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_ERK_PATHWAY