Details for gene set REACTOME_ENDOGENOUS_STEROLS[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_Cyp2c44KO.RPKM_matrix___PanKO_vs_Cyp2c44KO.cls #PanKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___PanKO_vs_Cyp2c44KO.cls#PanKO_versus_Cyp2c44KO
Upregulated in class	Cyp2c44KO
GeneSet	REACTOME_ENDOGENOUS_STEROLS
Enrichment Score (ES)	-0.44449404
Normalized Enrichment Score (NES)	-1.1554608
Nominal p-value	0.115303986
FDR q-value	1.0
FWER p-Value	0.972

Fig 1: Enrichment plot: REACTOME_ENDOGENOUS_STEROLS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Cyp1b1	na	1532	0.861	0.0416	No
2	Arnt2	na	2822	0.654	0.0711	No
3	Cyp11a1	na	2932	0.641	0.1204	No
4	Ptgis	na	3015	0.631	0.1694	No
5	Cyp11b1	na	3756	0.555	0.2006	No
6	Cyp51	na	5031	0.451	0.2140	No
7	Arnt	na	6005	0.386	0.2277	No
8	Cyp39a1	na	6033	0.385	0.2580	No
9	Cyp21a1	na	7329	0.311	0.2599	No
10	Cyp7b1	na	11893	0.105	0.1873	No
11	Ahrr	na	12725	0.076	0.1786	No
12	Fdx2	na	13800	0.039	0.1627	No
13	Cyp11b2	na	14075	0.031	0.1603	No
14	Cyp19a1	na	33801	0.000	-0.1897	No
15	Ncoa2	na	45308	-0.026	-0.3918	No
16	Cyp4v3	na	47748	-0.107	-0.4266	No
17	Rxra	na	48758	-0.152	-0.4324	Yes
18	Ncoa1	na	49192	-0.173	-0.4263	Yes
19	Ahr	na	49353	-0.180	-0.4147	Yes
20	Pomc	na	50400	-0.235	-0.4144	Yes
21	Nr1h4	na	52004	-0.335	-0.4161	Yes
22	Fdx1	na	53585	-0.470	-0.4065	Yes
23	Fdxr	na	54980	-0.675	-0.3773	Yes
24	Cyp27a1	na	55467	-0.802	-0.3218	Yes
25	Cyp7a1	na	55887	-0.987	-0.2503	Yes
26	Cyp46a1	na	55921	-1.005	-0.1705	Yes
27	Cyp8b1	na	56368	-2.234	0.0002	Yes

Fig 2: REACTOME_ENDOGENOUS_STEROLS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_ENDOGENOUS_STEROLS: Random ES distribution   
Gene set null distribution of ES for REACTOME_ENDOGENOUS_STEROLS