Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | RPKM_matrix___PanKO_vs_Cyp2c44KO.RPKM_matrix___PanKO_vs_Cyp2c44KO.cls #PanKO_versus_Cyp2c44KO |
| Phenotype | RPKM_matrix___PanKO_vs_Cyp2c44KO.cls#PanKO_versus_Cyp2c44KO |
| Upregulated in class | Cyp2c44KO |
| GeneSet | WP_TRYPTOPHAN_METABOLISM |
| Enrichment Score (ES) | -0.5541852 |
| Normalized Enrichment Score (NES) | -1.199072 |
| Nominal p-value | 0.18128654 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.866 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | Aldh1a2 | na | 825 | 1.063 | 0.0375 | No |
| 2 | Prmt1 | na | 959 | 1.012 | 0.0848 | No |
| 3 | Cyp1b1 | na | 1532 | 0.861 | 0.1169 | No |
| 4 | Wars1 | na | 3022 | 0.630 | 0.1214 | No |
| 5 | Mdm2 | na | 5278 | 0.432 | 0.1026 | No |
| 6 | Aoc1 | na | 6547 | 0.353 | 0.0974 | No |
| 7 | Acmsd | na | 6795 | 0.340 | 0.1097 | No |
| 8 | Rnf25 | na | 6905 | 0.333 | 0.1241 | No |
| 9 | Dhcr24 | na | 7295 | 0.313 | 0.1326 | No |
| 10 | Cyp2f2 | na | 8073 | 0.274 | 0.1322 | No |
| 11 | Cyp2j6 | na | 8335 | 0.262 | 0.1404 | No |
| 12 | Cyp1a2 | na | 10244 | 0.178 | 0.1153 | No |
| 13 | Ubr5 | na | 10260 | 0.177 | 0.1237 | No |
| 14 | Cyp7b1 | na | 11893 | 0.105 | 0.0999 | No |
| 15 | Ogdh | na | 12303 | 0.092 | 0.0971 | No |
| 16 | Asmt | na | 13243 | 0.058 | 0.0833 | No |
| 17 | Aadat | na | 14269 | 0.026 | 0.0664 | No |
| 18 | Tph1 | na | 19487 | 0.000 | -0.0262 | No |
| 19 | Cyp19a1 | na | 33801 | 0.000 | -0.2803 | No |
| 20 | Aanat | na | 35149 | 0.000 | -0.3042 | No |
| 21 | Aox1 | na | 48761 | -0.152 | -0.5384 | No |
| 22 | Cyp1a1 | na | 48806 | -0.154 | -0.5316 | No |
| 23 | Ube3a | na | 48935 | -0.160 | -0.5260 | No |
| 24 | Echs1 | na | 50365 | -0.233 | -0.5400 | No |
| 25 | Kynu | na | 51166 | -0.281 | -0.5404 | Yes |
| 26 | Aldh2 | na | 51168 | -0.281 | -0.5267 | Yes |
| 27 | Maob | na | 51499 | -0.301 | -0.5178 | Yes |
| 28 | Cyp4f14 | na | 51886 | -0.327 | -0.5086 | Yes |
| 29 | Ddc | na | 52027 | -0.337 | -0.4945 | Yes |
| 30 | Ido1 | na | 52297 | -0.357 | -0.4818 | Yes |
| 31 | Aldh1a1 | na | 52550 | -0.376 | -0.4678 | Yes |
| 32 | Hsd17b10 | na | 52717 | -0.389 | -0.4517 | Yes |
| 33 | Hadh | na | 53560 | -0.467 | -0.4437 | Yes |
| 34 | Inmt | na | 53597 | -0.472 | -0.4212 | Yes |
| 35 | Cat | na | 54514 | -0.591 | -0.4085 | Yes |
| 36 | Aldh9a1 | na | 54686 | -0.619 | -0.3811 | Yes |
| 37 | Acat1 | na | 54760 | -0.631 | -0.3515 | Yes |
| 38 | Tdo2 | na | 54768 | -0.633 | -0.3205 | Yes |
| 39 | Gcdh | na | 54958 | -0.669 | -0.2910 | Yes |
| 40 | Haao | na | 54968 | -0.672 | -0.2582 | Yes |
| 41 | Aldh3a2 | na | 55232 | -0.738 | -0.2267 | Yes |
| 42 | Cyp2e1 | na | 55850 | -0.968 | -0.1901 | Yes |
| 43 | Afmid | na | 55875 | -0.983 | -0.1423 | Yes |
| 44 | Cyp2c55 | na | 56372 | -3.082 | 0.0001 | Yes |
