Details for gene set REACTOME_ENDOGENOUS_STEROLS[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_WT.RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Phenotype	RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Upregulated in class	WT
GeneSet	REACTOME_ENDOGENOUS_STEROLS
Enrichment Score (ES)	-0.4622003
Normalized Enrichment Score (NES)	-1.1648256
Nominal p-value	0.1030303
FDR q-value	0.76254576
FWER p-Value	0.988

Fig 1: Enrichment plot: REACTOME_ENDOGENOUS_STEROLS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Arnt2	na	1761	0.855	0.0396	No
2	Cyp1b1	na	2319	0.759	0.0926	No
3	Cyp11a1	na	3098	0.664	0.1339	No
4	Ptgis	na	3503	0.620	0.1781	No
5	Arnt	na	3972	0.578	0.2177	No
6	Ahrr	na	4604	0.524	0.2499	No
7	Cyp21a1	na	5537	0.458	0.2713	No
8	Ncoa2	na	8044	0.310	0.2525	No
9	Cyp39a1	na	8108	0.306	0.2768	No
10	Cyp11b2	na	10018	0.217	0.2609	No
11	Fdx2	na	10021	0.217	0.2788	No
12	Cyp4v3	na	11061	0.170	0.2745	No
13	Cyp11b1	na	16223	0.020	0.1845	No
14	Cyp7b1	na	16298	0.019	0.1848	No
15	Ncoa1	na	16564	0.015	0.1813	No
16	Cyp19a1	na	35417	0.000	-0.1532	No
17	Ahr	na	47918	-0.017	-0.3736	No
18	Rxra	na	49022	-0.050	-0.3891	No
19	Pomc	na	53145	-0.263	-0.4404	Yes
20	Cyp51	na	54295	-0.354	-0.4315	Yes
21	Fdxr	na	54312	-0.356	-0.4023	Yes
22	Fdx1	na	55184	-0.474	-0.3784	Yes
23	Nr1h4	na	55554	-0.549	-0.3395	Yes
24	Cyp27a1	na	56169	-0.813	-0.2830	Yes
25	Cyp46a1	na	56235	-0.911	-0.2087	Yes
26	Cyp7a1	na	56266	-0.966	-0.1291	Yes
27	Cyp8b1	na	56369	-1.582	0.0001	Yes

Fig 2: REACTOME_ENDOGENOUS_STEROLS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_ENDOGENOUS_STEROLS: Random ES distribution   
Gene set null distribution of ES for REACTOME_ENDOGENOUS_STEROLS